Retained splenic function in an indian population with homozygous sickle cell disease may have important clinical significance

Conclusions: The maximal risk of invasive pneumococcal infection in SS disease falls sharply after the age of 3 years, and persistence of splenic function in Odisha patients beyond this age may explain the apparent absence of pneumococcal septicemia in Indian patients and questions the role of pneumococcal prophylaxis.
Source: Indian Journal of Community Medicine - Category: International Medicine & Public Health Authors: Source Type: research