Messenger RNA vaccines and neutralizing anti-severe acute respiratory syndrome coronavirus 2 antibodies in patients with immunodeficiency

Ann Allergy Asthma Immunol. 2021 Dec;127(6):703. doi: 10.1016/j.anai.2021.09.007.NO ABSTRACTPMID:34823756 | PMC:PMC8608549 | DOI:10.1016/j.anai.2021.09.007
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research

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AbstractThe outbreak of the coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become an evolving global health crisis. Currently, a number of risk factors have been identified to have a potential impact on increasing the morbidity of COVID-19 in adults, including old age, male sex, pre-existing comorbidities, and racial/ethnic disparities. In addition to these factors, changes in laboratory indices  and pro-inflammatory cytokines, as well as possible complications, could indicate the progression of COVID-19 into a severe and critical stage. Child...
Source: Clinical Reviews in Allergy and Immunology - Category: Allergy & Immunology Source Type: research
Coronavirus disease of 2019 (COVID-19) is a respiratory illness characterized by fever, cough, dyspnea, fatigue, and lymphopenia. Severe COVID-19 complications can manifest as viral pneumonia and may lead to severe acute respiratory syndrome and, in some cases, death [1, 2]. As of December 2021, SARS-CoV-2 has caused more than 263,300,000 infections, and over 5,221,000 deaths. Since December 2020, over 8,033,000,000 vaccine doses have been administered [3]. A global systematic review conducted during the COVID-19 pandemic of the general public's psychological outcomes found relatively high rates of anxiety (6.33% to 50.9%)...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research
Iran J Allergy Asthma Immunol. 2021 Dec 8;20(6):647-671. doi: 10.18502/ijaai.v20i6.8016.ABSTRACTThe widespread outbreak of coronavirus disease 2019 in late 2019 caused many people worldwide to die or suffer from certain clinical complications even after the recovery. The virus has many social and economic adverse effects. Studies on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have specified that spike, surface glycoprotein antigen, is considered as a major target to stimulate the immune system. This glycoprotein binds to the angiotensin-converting enzyme 2 on the surface of human cells especially lung epit...
Source: Iranian Journal of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
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