Sleep Apnea and Stroke

Publication date: Available online 14 March 2015 Source:Canadian Journal of Cardiology Author(s): Owen D. Lyons , Clodagh M. Ryan Stroke is the second leading cause of death worldwide and often has devastating consequences for affected individuals in terms of chronic disability. Traditional risk factors such as age, male sex, ethnicity, hypertension and atrial fibrillation explain 60-80% of the risk of stroke. Obstructive sleep apnea (OSA) is highly prevalent in the post-stroke population and its emerging role as a potential modifiable risk factor for stroke has been recognised in the most recent American Heart Association stroke guidelines which recommend consideration of both screening for and treatment of OSA in this regard. In this paper we provide an overview of the current evidence based knowledge relating to stroke and sleep apnea. The main focus of this paper is to consider key pathophysiological mechanisms by which obstructive sleep apnea may increase the risk for stroke. The effect of OSA on stroke outcomes and the efficacy of treatment of OSA on these outcomes is also considered. Teaser Sleep apnea has been postulated as a significant causative intermediary mechanism of stroke. It is prevalent in the post-stroke population. In this article we will provide a synopsis of current evidence exploring the relationship between sleep apnea and stroke.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research