Alteration of gut microbial composition associated with the therapeutic efficacy of fecal microbiota transplantation in Clostridium difficile infection

CONCLUSION: Gut dysbiosis commonly co-exists in patients with rCDI. Restoration of gut microbial communities by FMT provides a promising strategy to treat antibiotic-failed CDI, and the extent of microbial change would be related to the treatment outcomes of FMT. Besides, the effectiveness of FMT for CDI could be maintained even the gut microbiota has diverged over time.PMID:34836663 | DOI:10.1016/j.jfma.2021.11.001

Source: J Formos Med Assoc - November 27, 2021 Category: General Medicine Authors: Pei-Chang Lee Tien-En Chang Yen-Po Wang Kuei-Chuan Lee Yi-Tsung Lin Jen-Jie Chiou Chi-Wei Huang Ueng-Cheng Yang Fen-Yau Li Hui-Chun Huang Chun-Ying Wu Yi-Hsiang Huang Ming-Chih Hou Source Type: research