LSC - 2021 - COL4A3 expression in asthmatic epithelium depends on intronic methylation and ZNF263 binding

Conclusion: Our data suggests an epigenetic modification at cg11797365 interrupts ZNF263 binding which may contribute to the COL4A3 expression deficit in asthmatic airways.

Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Sai Sneha Priya, N., Joseph Vermeulen, C., Pech, M., Faiz, A., George G. Oliver, B., Van Den Berge, M., Kay Burgess, J., Kopp, M., Weckmann, M. Tags: Occupational and environmental health Source Type: research