CCR5 antagonist reduces HIV-induced amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations in HIV-infected hu-PBL-NSG mice

Neurocognitive impairment is present in 50% of HIV-infected individuals and is often associated with Alzheimer ’s Disease (AD)-like brain pathologies, including increased amyloid-beta (Aβ) and Tau hyperphosphor...
Source: Molecular Neurodegeneration - Category: Neurology Authors: Tags: Research article Source Type: research