Combigraft versus Bio ‐Oss/Bio‐Gide in alveolar ridge preservation: A prospective randomized controlled trial

AbstractThe aim of this prospective study was to compare Combigraft with Bio-Oss/Bio-Gide complex in alveolar bone preservation in terms of clinical, laboratory and radiographic outcomes in a randomised controlled trial. 80 patients undergoing tooth extraction with the requirement of alveolar bone preservation were randomly allocated to the experimental and control groups. A total of 75 patients completed the study; 37 in the experimental group and 38 in the control group. Two patients who did not fully complete the study but had at least one record on the follow-up period were analysed, significantly, 73 teeth among 77 dental sites were mandibular third molars which accounted for 94.8% of all subjects in this study. Bone grafting was performed using either of Combigraft or Bio-Oss/Bio-Gide complex. The primary outcome was to compare the height and width of alveolar ridge between immediate postoperation and six months postoperation by radiographic evaluation. A two-samplet-test was used for independent samples for quantitative variables (such as age) and a chi-square statistic was used for nominal parameters. Six months after surgery, the height and width of alveolar ridge were 9.47  ± 1.61 mm and 14.71 ± 1.99 mm respectively using Combigraft while those were 9.82 ± 2.04 mm and 14.83 ± 2.04 mm respectively in the control group. There was no significant difference in the total effective rate between the two groups. Combigraft appears to be an alternative option...
Source: Oral Surgery - Category: ENT & OMF Authors: Tags: ORIGINAL ARTICLE Source Type: research