Spirochetal uveitis: Spectrum of clinical manifestations, diagnostic and therapeutic approach, final outcome and epidemiological data

ConclusionDespite being rare, spirochetal uveitis can be detrimental for the vision and must always be included in the differential diagnosis.
Source: International Ophthalmology - Category: Opthalmology Source Type: research

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Conclusion Exposure to ANCS was associated with higher survival rates to 1 YOL among resuscitated infants born at 22 and 23 weeks. National guidelines recommending against ANCS utilization at 22 weeks should be re-evaluated given emerging evidence of benefit. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research
Environ Sci Pollut Res Int. 2021 Nov 27. doi: 10.1007/s11356-021-17723-9. Online ahead of print.ABSTRACTThe occurrence of antibiotics in drinking water resources, like reservoirs, is of considerable concern due to their potential risks to ecosystem, human health, and antimicrobial resistance development. Here, we quantified 83 antibiotics in water and sediments of wet and dry seasons from the Miyun reservoir and its inflow rivers in Beijing, China. Twenty-four antibiotics were detected in water with concentrations of ND-11.6 ng/L and 19 antibiotics were observed in sediments with concentrations of ND-6.50 ng/g. Sulfonamide...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Source Type: research
CONCLUSIONS: Higher doses of dexamethasone not only failed to improve efficacy but also resulted in an increase in the number of adverse events and worsen survival in hospitalized patients with moderate to severe COVID-19 compared to the low-dose dexamethasone. (IRCT20100228003449N31).PMID:34837648 | DOI:10.1007/s43440-021-00341-0
Source: Pharmacological Reports - Category: Drugs & Pharmacology Authors: Source Type: research
We present four clinical cases of post-surgical CME (three following vitrectomy and one following cataract surgery in a vitrectomized eye 2 years ago). All of them had been previously treated with an average of four injections of intravitreal dexamethasone implant (Ozurdex®), with repeated recurrence of CME. After treatment with Iluvien, three cases showed improvement of both visual acuity and macular anatomy, with resolution of the macular edema. One patient required additional treatment with Ozurdex during follow-up, further improving CME. Two of the cases required topical pressure lowering treatment, and none requir...
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
In COVID-19 clinical update #90, Dr. Griffin covers FDA expansion for booster doses, 3 more at home antigen tests approved by FDA, immune correlates analysis of mRNA-1273 vaccine, risk for stillbirth, PROVENT prophylaxis trial results, fluvoxamine recommendations, advice on molnupiravir, automated text messaging service for monitoring illness, and long COVID-19 after vaccination and infection. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Expanded eligibility for booster doses (FDA) M...
Source: This Week in Virology - MP3 Edition - Category: Virology Authors: Source Type: podcasts
Lyme borreliosis is a multi-organ disease primarily transmitted by ticks. The condition is endemic in different parts of Europe and North America, and is caused by the spirochetes Borrelia burgdorferi sensu stricto, Borrelia garinii and Borrelia afzelii. Nervous system manifestations termed Lyme neuroborreliosis (LNB) are seen in 10 –15% of all borrelia infections in adults. The most common manifestations are meningoradiculitis and cranial neuritis (Summer and Rupprecht, 2019). Rarer neurological complications include brain and spinal cord involvement, cerebral vasculitis and peripheral neuropathies (Moser, Bubel et al.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Case Report Source Type: research
CONCLUSIONS: Lyme disease is rare, but must be kept in mind when investigating the etiology of chorioretinitis and retinal vasculitis. The patient reported here is, to our knowledge, the second case reported in literature that shows atypical clinic for Lyme disease with unilateral chorioretinitis without Erythema chronicum migrans (ECM). PMID: 32998513 [PubMed - as supplied by publisher]
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Eur J Ophthalmol Source Type: research
CONCLUSIONS: Lyme Neuroborreliosis accounts for a small proportion of paediatric stroke even in an endemic country. The strong predilection towards posterior cerebral circulation with clinical occurrence of brainstem signs associated with meningeal symptoms and CSF lymphocytosis are suggestive features that should rapidly point to the diagnosis. This can confirmed by appropriate serological testing in the serum and CSF. Clinicians must be aware of this rare neurological complication of Lyme disease that demands specific antibiotic treatment. PMID: 29208342 [PubMed - as supplied by publisher]
Source: European Journal of Paediatric Neurology - Category: Neurology Authors: Tags: Eur J Paediatr Neurol Source Type: research
Lyme neuroborreliosis (LNB) is a disease of the nervous system caused by the spirochete Borrelia burgdorferi sensu lato genospecies, which is transmitted by the bite of infected ticks. Approximately 15% of patients with Lyme borreliosis develop neurological manifestations; most frequently meningitis, cranial neuritis or polyradiculitis [1]. Ischemic stroke due to cerebral vasculitis is rarely (
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
CONCLUSIONS: Clinical diagnosis of PNGD is difficult, and is based mainly on the histopathological picture. Systemic therapy is incorporated mainly due to the systemic disease. The patient requires further observation in the direction of associated systemic disorders. PMID: 27294654 [PubMed - in process]
Source: Annals of Agricultural and Environmental Medicine : AAEM - Category: Environmental Health Authors: Tags: Ann Agric Environ Med Source Type: research
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