The role of potassium in muscle membrane dysfunction in end-stage renal disease

CONCLUSIONS: In ESRD patients, the muscle membrane is depolarized, mainly due to hyperkalemia.SIGNIFICANCE: Since normal muscle fatigue has been attributed to potassium-induced depolarization, it seems likely that this mechanism is also a major cause of the exaggerated muscle fatigue and weakness in ESRD patients.PMID:34740043 | DOI:10.1016/j.clinph.2021.09.012

Source: Clinical Neurophysiology - November 5, 2021 Category: Neurology Authors: Lotte Hardbo Larsen Werner J Z'Graggen Hugh Bostock S Veronica Tan Niels Henrik Buus Hatice Tankisi Source Type: research