Innate and adaptive abnormalities in youth with vertically acquired HIV through a multicentre cohort in Spain

CONCLUSIONS: Immunological changes associated with vertically acquired HIV, characterized by increased activation and exhaustion levels in innate and adaptive immune components, are only partially restored by ART. The CD4/CD8 ratio can be a useful marker of disease progression for routine clinical practice.PMID:34672108 | DOI:10.1002/jia2.25804

Source: Journal of the International AIDS Society - October 21, 2021 Category: Infectious Diseases Authors: Itz íar Carrasco Laura Tarancon-Diez Elena V ázquez-Alejo Santiago Jim énez de Ory Tal ía Sainz Miren Apilanez Cristina Epalza Sara Guill én Jos é Tomás Ramos Cristina D íez Jose Ignacio Bernardino Jos é Antonio Iribarren Angielys Zamora Mar ía Source Type: research