The Role of Vascular Endothelial Growth Factor in Tendon Healing

This article will summarize the role of both endogenous and exogenous VEGF in tendon healing and discuss possible reasons for the controversy. The present review shows that tendon repair is facilitated only by proper angiogenesis and VEGF at the early stage, whereas the persistent high VEGF expression and prolonged presence of blood vessels may impair tendon repair at a later stage.
Source: Frontiers in Physiology - Category: Physiology Source Type: research