Elevated magnetic resonance imaging measures of adipose tissue deposition in women with breast cancer treatment-related lymphedema

AbstractPurposeBreast cancer treatment-related lymphedema (BCRL) is a common co-morbidity of breast cancer therapies, yet factors that contribute to BCRL progression remain incompletely characterized. We investigated whether magnetic resonance imaging (MRI) measures of subcutaneous adipose tissue were uniquely elevated in women with BCRL.MethodsMRI at 3.0  T of upper extremity and torso anatomy, fat and muscle tissue composition, andT2 relaxometry were applied in left and right axillae of healthy control (n = 24) and symptomatic BCRL (n = 22) participants to test the primary hypothesis that fat-to-muscle volume fraction is elevated in symptomatic BCRL relative to healthy participants, and the secondary hypothesis that fat-to-muscle volume fraction is correlated with MR relaxometry of affected tissues and BCRL stage (significan ce criterion: two-sidedp 
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research

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Clin J Oncol Nurs. 2021 Dec 1;25(6):29. doi: 10.1188/21.CJON.S2.29.ABSTRACTFor lymphedema, standards of care are based on established evidence-based practice. Lymphedema is the accumulation of lymph fluid that obstructs the flow of the lymphatic system, causing persistent swelling of the affected body part. Lymphedema is most commonly seen after lymph node dissection or radiation therapy. It occurs in 10%-40% of patients with breast cancer and 80% of patients with lymph node dissection in the groin.PMID:34800126 | DOI:10.1188/21.CJON.S2.29
Source: Clinical Journal of Oncology Nursing - Category: Nursing Authors: Source Type: research
Lymphatic Research and Biology, Ahead of Print.
Source: Lymphatic Research and Biology - Category: Biology Authors: Source Type: research
DiscussionBased on the results that MT has an influence on shoulder function immediately after intervention in patients without nerve injury, this randomized controlled trial is to observe the efficacy of MT on shoulder function after a long-term intervention in breast cancer survivors. We look forward to the innovation of this study for both breast cancer rehabilitation and MT.Trial registrationChinese Clinical Trial Registry (ChiCTR) ChiCTR2000033080. Registered on 19 May 2020
Source: Trials - Category: Research Source Type: clinical trials
Condition:   Breast Cancer Lymphedema Interventions:   Procedure: axillary lymph node dissection with vein branches reservation;   Procedure: axillary lymph node dissection without vein branches reservation Sponsor:   Xiangyun Zong Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Condition:   Breast Cancer Lymphedema Intervention:   Other: Exercise guideline Sponsor:   Isabel Lopez Zamora Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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