Utilizing the Left Gastric Varix As the Preferred Conduit for Severe Portal Vein Thrombosis in Liver Transplantation

For patients with severe portal vein thrombosis (PVT), an SMV conduit is usually considered the primary reconstruction option. A left gastric varix (LGV) conduit reconstruction is an alternative which we prefer because it requires less dissection and has less risk of tension and torsion. The aim of this study was to compare the outcomes of patients using an SMV conduit to those using a gastric varix conduit.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Transplantation and Tissue Engineering Source Type: research

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Conditions:   Portal Vein Thrombosis;   Liver Transplant; Complications Interventions:   Procedure: living donor liver transplantation;   Procedure: Thrombectomy or interposition graft Sponsors:   Elvan Onur Kirimker;   Ankara University;   Ankara Guven Hospital Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractThe relationship between acidosis and coagulopathy has long been described in vitro and in trauma patients, but not yet in orthotopic liver transplantation (OLT). The association of metabolic acidosis with coagulopathy and with transfusion requirements was evaluated in patients submitted to OLT. Changes in acid-base and coagulation parameters were analyzed by repeated measures. Regression analyses [adjusted for sex, age, model for end stage liver disease (MELD) score, and baseline values of hemoglobin, fibrinogen, international normalized ratio, platelets] determined the association of acid-base parameters with coa...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
We describe failure of DOACs to prevent post-TIPS complications in two case reports of patients with MPN-associated pHTN and review the associated literature. We conducted a comprehensive search in Embase (embase.com), Scopus (scopus.org), and PubMed for existing data on MPN-associated pHTN post-TIPS procedure. Four studies (n = 251) of patients with pHTN post-TIPS were eligible (MPN, n = 143). A review of the literature suggests that patients with MPN-associated pHTN may be at higher risk for post-TIPS complications including stent thrombosis and stenosis, compared with other causes of thrombotic pHTN. DOAC use ha...
Source: Blood Coagulation and Fibrinolysis - Category: Hematology Tags: ORIGINAL ARTICLES Source Type: research
AbstractA new onset acute heart failure (HF) with a sudden drop in the left ventricular ejection fraction (LVEF) post orthotopic liver transplant (LT) is a rare but a potentially fatal complication. Because in most of the cases there is no evidence of coronary thrombosis, it can be classified as nonischemic cardiomyopathy. More specifically, clinical presentation of this syndrome shares many features with stress-induced or takotsubo cardiomyopathy. The known factors that predispose these patients to acute HF during or shortly after LT include cirrhotic cardiomyopathy, rapid hemodynamic changes during LT surgery, and the la...
Source: Heart Failure Reviews - Category: Cardiology Source Type: research
We report the case of a 73-year-old male, with a history of liver cirrhosis secondary to hepatitis C virus (HCV). Due to this condition he underwent a liver transplant (LT) in 1993. From then on he was given immunosuppressive treatment with cyclosporin in monotherapy.PMID:34779217 | DOI:10.17235/reed.2021.8395/2021
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Authors: Source Type: research
We report a 65-year-old female patient with disseminated brain abscesses caused by Fusarium after liver transplantation (LT). The patient underwent LT for secondary sclerosing cholangitis after acute respiratory distress syndrome (ARDS). After a complicated course with aneurysm and thrombosis of the hepatic artery, re-transplantation was performed after one month. Due to inadequate awakening response, cerebral imaging was performed, which showed multiple abscesses. The patient died shortly thereafter, and an autopsy showed fusariosis.PMID:34781387 | DOI:10.1055/a-1535-2981
Source: Zeitschrift fur Gastroenterologie - Category: Gastroenterology Authors: Source Type: research
We report the case of a 73-year-old male, with a history of liver cirrhosis secondary to hepatitis C virus (HCV). Due to this condition he underwent a liver transplant (LT) in 1993. From then on he was given immunosuppressive treatment with cyclosporin in monotherapy.PMID:34779217 | DOI:10.17235/reed.2021.8395/2021
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Authors: Source Type: research
RARITAN, N.J., November 4, 2021 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today that more than 45 company-sponsored abstracts, including 11 oral presentations, plus more than 35 investigator-initiated studies will be featured at the American Society of Hematology (ASH) Annual Meeting and Exposition. ASH is taking place at the Georgia World Congress Center in Atlanta and virtually from December 11-14, 2021.“We are committed to advancing the science and treatment of hematologic malignancies and look forward to presenting the latest research from our robust portfolio and pipeline dur...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
J Inflamm Res. 2021 Oct 22;14:5443-5450. doi: 10.2147/JIR.S328334. eCollection 2021.ABSTRACTOBJECTIVE: To explore the feasibility of treating cirrhosis using a multidisciplinary team approach (MDT) and to pinpoint the key factors influencing its implementation.METHODS: The data of 307 patients with decompensated cirrhosis were studied retrospectively. Patients who received more than two treatment measures were assigned to the MDT group (n=228), and patients who received symptomatic medical drug treatment only were assigned to the traditional treatment group (n=79). The follow-up period ranged from 4 to 10 years, and the av...
Source: Cell Research - Category: Cytology Authors: Source Type: research
Intern Med. 2021 Oct 26. doi: 10.2169/internalmedicine.8226-21. Online ahead of print.ABSTRACTA series of abdominal computed tomography scans of an asymptomatic 40-year-old woman with a history of umbilical cord blood transplantation (CBT) for leukemia at 19 years old revealed the long-term gradual development of a right hepatic vein thrombus and stenosis of the inferior vena cava, leading to a diagnosis of Budd-Chiari syndrome. The Budd-Chiari syndrome in this case might have been influenced by the patient's history of multiple liver abscesses after CBT and associated thrombus formation, in addition to the hormone replace...
Source: Internal Medicine - Category: Internal Medicine Authors: Source Type: research
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