Glucocorticoids inhibit human hematopoietic stem cell differentiation toward a common ILC precursor

Capsule summary: GC treatment in patients receiving HSCT acts on HSC and induces a defect in hILCs development, which may affect innate defense against pathogens and the homeostasis of mucosal tissues.

Source: Journal of Allergy and Clinical Immunology - October 21, 2021 Category: Allergy & Immunology Authors: Linda Quatrini, Nicola Tumino, Francesca Besi, Cecilia Ciancaglini, Federica Galaverna, Antonio Giacomo Grasso, Pietro Merli, Franco Locatelli, Paola Vacca, Lorenzo Moretta Source Type: research