Could Soluble Endothelial Protein C Receptor Levels Recognize SARS-CoV2-Positive Patients Requiring Hospitalization?

In this study, we investigated whether sEPCR levels were related to COVID-19 patients’ requirement for hospitalization. Methods: Plasma sEPCR levels were measured on hospital admission in 84 COVID-19 patients, and in 11 non-hospitalized SARS-CoV2-positive patients approximately 6 days after reported manifestation of their symptoms. Multiple logistic regression analysis was performed to identify potential risk factors for hospitalization and receiver operating characteristic (ROC) curves were generated to assess their value. Results: In our cohort, hospitalized patients had considerably higher sEPCR levels upon admission compared with outpatients [107.5 (76.7–156.3) vs. 44.6 (12.1–84.4) ng/mL; P 
Source: Shock - Category: Emergency Medicine Tags: Clinical Science Aspects Source Type: research