Role of scavenger receptors in silica nanoparticle-induced cytokine responses in bronchial epithelial cells

In conclusion, LOX-1 and CXCL16 and especially SR-B1 seem to have important roles in mediating cytokine responses and TGF-α release due to SiNP exposure in BEAS-2B cells, without a down-stream role of MAP-kinase and NF-κB.PMID:34653535 | DOI:10.1016/j.toxlet.2021.10.004

Source: Toxicology Letters - October 15, 2021 Category: Toxicology Authors: Magne Refsnes Tonje Skuland Johan Øvrevik Marit L åg Source Type: research