Unilateral nephrocalcinosis

A 37-year-old man with unremarkable medical history was referred to our nephrology department for unilateral left nephrocalcinosis, incidentally discovered on imaging for chronic low back pain (Figure  1, arrow). On clinical examination, we were struck by a lateralized overgrowth of the left hemibody (Figure 2). An abdominal computed tomography scan with 3-dimensional reconstruction made the diagnosis of medullary sponge kidney (with precaliceal canalicular ectasia predominantly seen in the lef t kidney) and did not show any other abnormality (Supplementary Figure S1).
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Nephrology Image Source Type: research

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DISCUSSION: Intradiscal vacuum phenomenon was closely associated with severe IVDD, Modic changes, and SS. Further prospective clinical and laboratory studies are necessary to better delineate the pathogenesis of IVP.PMID:34663160 | DOI:10.1080/03007995.2021.1994379
Source: Current Medical Research and Opinion - Category: Research Authors: Source Type: research
Conclusion. The present case demonstrated the need to extensively investigate causes of generalized bone pain in patients with hypophosphatemia, as TIO is highly curable. Importantly, 68Ga-DOTATATE PET/CT imaging successfully identified the FGF23 producing tumor, which was undetectable by conventional imaging, favoring its early use in suspected TIO presentation. The present report highlights the importance of timely diagnosis of this complex medical condition, aiming to improve general awareness and enable better clinical outcomes for this rare disorder.PMID:34523297 | DOI:10.2478/enr-2021-0017
Source: Endocrine Regulations - Category: Endocrinology Authors: Source Type: research
More News: Back Pain | Chronic Pain | CT Scan | Low Back Pain | Pain | PET Scan | Urology & Nephrology