GSE186089 Replication of Dengue virus in differentiating K562-megakaryocytes is promoted by virus induced suppression in the accumulation of reactive oxygen species

Contributors : Kaur Jaskaran ; Rawat Yogita ; Sood Vikas ; Periwal Neha ; Rathore Deepak ; Kumar Shrikant ; Kumar Niraj ; Bhattacharyya SankarSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensOur study reports that over-expression of NRf2 target genes causes reduction in the ROS accumulation in differentiating cells which ultimately enhances Dengue virus replication and we also report the suppression of cell adhesion molecules and platelet specific surface markers in Dengue virus infected K562-megakaryocyte cells.

Source: GEO: Gene Expression Omnibus - October 20, 2021 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research