Associations Between Maternal Depression, Antidepressant Use During Pregnancy, and Adverse Pregnancy Outcomes: An Individual Participant Data Meta-analysis

CONCLUSION: Depressive symptoms or a clinical diagnosis of depression during pregnancy are associated with preterm birth and low Apgar scores, even without exposure to antidepressants. However, SSRIs may be independently associated with preterm birth and low Apgar scores.SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42016035711.PMID:34623076 | DOI:10.1097/AOG.0000000000004538

Source: Obstetrics and Gynecology - October 8, 2021 Category: OBGYN Authors: Richelle Vlenterie Marleen M H J van Gelder H Ross Anderson Liselott Andersson Birit F P Broekman Gal Dubnov-Raz Hanan El Marroun Ema Ferreira Emma Fransson Frank M M A van der Heijden Claudia B Holzman J Jo Kim Ali S Khashan Betty R Kirkwood Harold J H K Source Type: research