Increased duodenal iron absorption through upregulation of DMT1 due to enhancement of IRP1 activity in patients with NASH

Conclusion: In spite of elevation of serum hepcidin, iron absorption from the gastrointestinal tract increased through upregulation of DMT1, via IRP1 activation by humoral factor(s) in the sera of patients with NASH. This article is protected by copyright. All rights reserved.

Source: Hepatology - March 7, 2015 Category: Internal Medicine Authors: Toshifumi Hoki, Koji Miyanishi, Shingo Tanaka, Kohichi Takada, Yutaka Kawano, Akira Sakurada, Masanori Sato, Tomohiro Kubo, Tsutomu Sato, Yasushi Sato, Rishu Takimoto, Masayoshi Kobune, Junji Kato Tags: Steatohepatitis and Metabolic Liver Disease Source Type: research