Reduced masticatory function predicts gastroesophageal reflux disease and esophageal dysphagia in patients referred for upper endoscopy: A cross-sectional study

The role of mastication on gastroesophageal reflux disease (GERD) is unknown.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Alimentary tract Source Type: research

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PPI-refractory gastroesophageal reflux disease (RGERD) is characterized as the existence of reflux symptoms resistant to optimized PPI treatment. Alleviated mucosal integrity has been regarded as one of the mechanisms of RGERD.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Alimentary Tract Source Type: research
AbstractPurpose of ReviewThere is increasing evidence on the connections between chronic oral inflammation/infection and the pathophysiological conditions of the gastrointestinal tract and accessory organs of digestion. The aim of this review is to provide a critical synthesis regarding the epidemiological, clinical, and in vivo associations between periodontitis and the most relevant diseases of the digestive system.Recent FindingsAn increasing body of dental and medical literature is supporting the gum-gut axis as a relevant mechanism to explain the associations between periodontitis and systemic diseases. Indeed, shared...
Source: Current Oral Health Reports - Category: Dentistry Source Type: research
Pediatric obesity is a chronic disease which leads to the development of significant health consequences in childhood, and increased risk of morbidity and premature mortality in adulthood. It is now estimated that 4% of children and 9% of adolescents in the United States have severe obesity (BMI ≥ 120% of the 95th percentile for age). (1) Causal factors for obesity include genetics, environment, medications, and behavior.(2) Severe obesity during childhood and adolescence is associated with the development of significant comorbidities such as cardiovascular disease, type 2 diabetes (T2D), obstructive sleep apnea (OSA), ...
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
Reflux esophagitis (RE) is a subset of gastroesophageal reflux disease (GERD) with endoscopic evidence of esophageal inflammation, which has been linked to an increased incidence of atrial fibrillation (AF). However, data on the effect of RE on patient outcomes is limited. We sought to examine the potential association of RE with outcomes of patients with AF in a nationwide study. The National Inpatient Sample (NIS) database was queried to identify hospitalized adult patients with AF and RE between 2010 and 2014. Primary outcomes included inpatient mortality, length of stay (LOS), and total hospital charges. AF related ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Side effects of long-term acid suppression have increased the scholars ’ interest in nonpharmacologic intervention.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Review Article Source Type: research
This article outlines the pulmonary manifestations of different GI, pancreatic, and liver diseases in children, including gastroesophageal reflux disease, inflammatory bowel disease, pancreatitis, alpha1-antitrypsin deficiency, nonalcoholic fatty liver disease, and complications of chronic liver disease (hepatopulmonary syndrome and portopulmonary hypertension).
Source: Pediatric Clinics of North America - Category: Pediatrics Authors: Source Type: research
AbstractPurpose of reviewThe Mediterranean diet (MD) initially gained notoriety because of its link to reduced cardiovascular disease but over time has been associated with lower metabolic disease (diabetes, hyperlipidemia, hypertension), cancer, and all-cause mortality. Here, we review the existing literature examining the MD in common gastrointestinal and liver diseases.Recent findingsThe composition of the MD is rich in anti-inflammatory micronutrients (omega-9/omega-3 fatty acids, resveratrol) and fiber which are thought to confer its positive effects. The MD can help reduce non-alcoholic fatty liver disease (NAFLD) in...
Source: Current Treatment Options in Gastroenterology - Category: Gastroenterology Source Type: research
The most recent iteration of the classifications for functional esophageal disorders, Rome IV, proposed relevant modifications of the previous definitions for Rome III. They specifically considered increased esophageal acid exposure as the marker of gastroesophageal reflux disease (GERD), including the remaining part of non-erosive reflux disease patients with normal acid in the group with functional alterations, considering both reflux hypersensitivity and functional heartburn. However, recent pathophysiological and therapeutic data suggest the need for a return to including reflux hypersensitivity in the GERD spectrum.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Review article Source Type: research
The most recent iteration of the classifications for functional esophageal disorders, Rome IV, proposed relevant modifications of the previous definitions for Rome III. They specifically considered increased esophageal acid exposure as the marker of gastroesophageal reflux disease (GERD), including the remaining part of non-erosive reflux disease patients with normal acid in the group with functional alterations, considering both reflux hypersensitivity and functional heartburn. However, recent pathophysiological and therapeutic data suggest the need for a return to including reflux hypersensitivity in the GERD spectrum.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Review article Source Type: research
lo FF Abstract Helicobacter pylori (H. pylori) is a bacterium that infects more than a half of world's population. Although it is mainly related to the development of gastroduodenal diseases, several studies have shown that such infection may also influence the development and severity of various extragastric diseases. According to the current evidence, whereas this bacterium is a risk factor for some of these manifestations, it might play a protective role in other pathological conditions. In that context, when considered the gastrointestinal tract, H. pylori positivity have been related to Inflammatory Bowel Dis...
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
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