The use of pegylated interferon a-2a in a cohort of Greek patients with mycosis fungoides
IFN a with its cytotoxic and immunological effects on tumorous T cells has been introduced in the treatment of cutaneous T-cell lymphoma since the 1980s. The reported experience (average response rates 45 –80%, further improved with combination schemes) is mostly based on the use of the recombinant IFN a-2a or IFN a-2b. However, these interferon formulations are no longer commercially available in Europe and therefore, the pegylated analogue (pegylated IFN a-2a, Pegasys; Hoffmann-La Roche) has been currently used to treat CTCLs.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Aikaterini Patsatsi, Evangelia Papadavid, Elisavet Georgiou, Aikaterini Kyriakou, Triantafyllia Koletsa, Chrysostomos Avgeros, Marios Koumourtzis, Kyriaki Lampadaki, Athanasios Tsamaldoupis, Elizabeth Lazaridou, Alexandros Stratigos, Vassiliki Nikolaou Tags: POSTER PRESENTATIONS: TREATMENTS Source Type: research
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