Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis

The objective of this study was to determine if mechanistic target of rapamycin (mTOR) inhibition with or without AMP-activated protein kinase (AMPK) activation can protect against primary, age-related OA.

Source: Arthritis Research and Therapy - October 7, 2021 Category: Rheumatology Authors: Dennis M. Minton, Christian J. Elliehausen, Martin A. Javors, Kelly S. Santangello and Adam R. Konopka Tags: Research article Source Type: research