Spontaneous recovery from sunitinib-induced disruption of sarcomere in human iPSC-cardiomyocytes and possible involvement of the Hippo pathway

Sunitinib is known to cause cardiotoxicity in clinical settings. However, among sunitinib-treated patients experiencing adverse cardiac events, decreased cardiac function was reportedly reversible in> 50% of ...

Source: BMC Clinical Pharmacology - October 6, 2021 Category: Drugs & Pharmacology Authors: Toshikatsu Matsui and Tadahiro Shinozawa Tags: Research Source Type: research