DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status

Current clinical guidelines suggest that breast cancers with low hormone receptor expression (LowHR) in 1 –10% of tumor cells should be regarded as hormone receptor positive. However, clinical data show that th...

Source: Clinical Epigenetics - October 3, 2021 Category: Research Authors: Philipp Jurmeister, Karsten Weber, Sonia Villegas, Thomas Karn, Michael Untch, Anne Thieme, Volkmar M üller, Eliane Taube, Peter Fasching, Wolfgang D. Schmitt, Frederik Marmé, Elmar Stickeler, Bruno V. Sinn, Paul Jank, Christian Schem, Frederick Klausch Tags: Research Source Type: research