Aqueous extract of < em > Petasites japonicus < /em > leaves promotes osteoblast differentiation via up-regulation of Runx2 and Osterix in MC3T3-E1 cells

CONCLUSIONS: These results suggest that AL can regulate osteoblasts differentiation, at least in part through Runx2 and Osterix. Therefore, it is highly likely that P. japonicus will be useful as an alternate therapeutic for the prevention and treatment of osteoporosis.PMID:34603606 | PMC:PMC8446688 | DOI:10.4162/nrp.2021.15.5.579

Source: Cell Research - October 4, 2021 Category: Cytology Authors: Eun Ji Kim Jae In Jung Young Eun Jeon Hyun Sook Lee Source Type: research