Mechanical Strain Regulates Myofibroblast Differentiation of Human Scleral Fibroblasts by YAP

In conclusion, mechanical strain activated scleral myofibroblast differentiation via YAP. The YAP pathway may play an important role in regulating scleral myofibroblast differentiation and ECM remodeling of the sclera in glaucoma.
Source: Frontiers in Physiology - Category: Physiology Source Type: research