Association between vesicoureteral reflux, urinary tract infection and antibiotics exposure in infancy and risk of childhood asthma

ConclusionThe nationwide retrospective cohort study demonstrated that short-term therapeutic dose of antibiotics for UTI in infants with or without VUR has a positive correlation with the prevalence of childhood asthma. Significant risk of childhood asthma was not observed when VUR cohort was exposed to long-term low-dose of prophylactic antibiotics.
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research

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AbstractPurposeTo systematically review the aetiological factors associated with molar incisor hypomineralisation (MIH). To this day, the aetiology remains unknown. Determining risk factors would allow risk assessment and enhance early diagnosis of MIH in young patients. The aim was to assess, evaluate and summarise the relationship between MIH and reported aetiological hypotheses.MethodsElectronic database searches of MEDLINE, EMBASE, EBSCO, LILACS and Cochrane Library were conducted. Authors conformed to PRISMA guidelines. Studies were screened, data extracted, assessment of risk of bias and calibration was completed by ...
Source: European Archives of Paediatric Dentistry - Category: Dentistry Source Type: research
ConclusionThis case report details the clinical course of sepsis secondary to pneumonia and urinary tract infection in the setting of Felty syndrome. Our patient does not fit the conventional profile for presentation given her race, age, and the length of time following diagnosis of rheumatoid arthritis.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
During the first six months of the pandemic, as people attempted to stay away from hospitals caring for those sick with COVID-19, potentially avoidable hospitalizations for non-COVID-19 –related conditions fell far more among white patients than Black patients, according to a new study that looked at admissions to UCLA Health hospitals.The findings indicate that the COVID-19 crisis has exacerbated existing racial health care disparities and suggest that during the pandemic, African Americans may have had worse access than whites to outpatient care that could have helped prevent deterioration of their non –COVID...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Vaccine. 2021 Mar 14:S0264-410X(21)00231-0. doi: 10.1016/j.vaccine.2021.02.051. Online ahead of print.ABSTRACTBACKGROUND: Streptococcus pneumoniae is the most frequent bacterial causative agent of pneumonia. Due to its significant contribution to the morbidity and mortality profile and the country's economy, the 10-valent pneumococcal vaccine (PCV10) was introduced in Brazil in 2010. Brazil is divided into five administrative regions which differ in social-economic indices among each other. Estimates of PCV10 impact on hospitalization rates due to pneumonia stratified by distinct Brazilian regions are limited. We assessed ...
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
Trimethoprim, a diaminopyrimidine compound, is a dihydrofolate reductase inhibitor. It is frequently used as a single agent for the treatment of uncomplicated urinary tract infections. It can be combined with sulfamethoxazole (as co-trimoxazole) for antimicrobial synergy. This combination is effective against a variety of gram-negative and gram-positive bacteria (including methicillin-resistant Staphylococcus aureus), some protozoa, and as prophylaxis against Pneumocystis jirovecii.(1)
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Discussion Lethargy is a common word used to describe a person who is drowsy, sluggish, listless and apathetic. Concentration may be difficult and they may have problems doing simple tasks. Many people actual mean fatigue or lassitude or being more tired when they use the word. In medical terms, lethargy is usually used to describe patients who have some type of excessive tiredness and usually have mental status changes with decreased alertness or arousal. Patients and health care providers both usually qualify the term and give more description to better communicate what is implied when using the term. This is true of man...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
CONCLUSIONS: Inequalities in paediatric hospital admissions exist for acute conditions and have not changed from 2003 to 2013; disadvantaged Victorian children were more likely to be admitted to hospital at each time point. More equitable access to medical and dental care is needed. Primary care (medical and dental) should be a critical platform to address socio-economic differences and effectively prevent avoidable hospital admissions in children. PMID: 33432713 [PubMed - as supplied by publisher]
Source: Rural Remote Health - Category: Rural Health Authors: Tags: J Paediatr Child Health Source Type: research
(American Academy of Family Physicians) When complications due to diabetes, asthma, urinary tract infections, high blood pressure and other common conditions lead patients to visit the ER, researchers and health care quality administrators may label these visits as " potentially preventable hospitalizations. " That is, with good outpatient care, these visits could have been potentially avoided. Potentially preventable hospitalizations are costly and can negatively impact the health and well-being of individuals, particularly if they are older.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Conclusion: AB, AB/FF users showed similar characteristics to those of other LAMA users. Compared with LABA and LABA/ICS users, AB and AB/FF users were older, had a higher frequency of severe COPD, chronic comorbidities, and use of COPD comedications.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
Conclusion: The results suggest that both maternal antibiotic use and infections during pregnancy, in addition to childhood exposures, have an independent role in the risk of offspring asthma.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
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