Overview of polyethylene glycol-based materials with a special focus on core-shell particles for drug delivery application

Curr Pharm Des. 2021 Sep 9. doi: 10.2174/1381612827666210910104333. Online ahead of print.ABSTRACTPolyethylene glycols (PEG) are water-soluble nonionic polymeric molecules. PEG and PEG-based materials are used for various important applications such as solvents, adhesives, adsorbents, drug delivery agents, tissue engineering scaffolds, etc. The coating of nanoparticles with PEG forms core-shell nanoparticles. The PEG-based core-shell nanoparticles are synthesized for the development of high-quality drug delivery systems. In the present review, we first explained the basics and various applications of PEGs and PEG-based composites materials and then concentrated on the PEG-based core-shell nanoparticles for biomedical applications specifically their use in drug delivery.PMID:34514984 | DOI:10.2174/1381612827666210910104333
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Source Type: research