Factors Associated with Affective Symptoms and Quality of Life in Patients with Atopic Dermatitis
Acta Derm Venereol. 2021 Sep 13. doi: 10.2340/00015555-3922. Online ahead of print.ABSTRACTThe aim of this study was to detect demographic and clinical factors associated with affective symptoms and quality of life in patients with severe atopic dermatitis. First, one-way analyses of variance and correlations were performed to compare a large set of qualitative and quantitative clinical variables. Three final multivariable regression models were performed, with depression/anxiety subscales and Dermatology Life Quality Index scores as dependent variables, and the factors that were statistically significant on univariate analyses as independent ones. More severe anxiety symptoms and poorer quality of life (p
ConclusionsAbrocitinib monotherapy improved disease-specific signs/symptoms and health-related quality of life across multiple domains as reported by adult and adolescent patients with moderate-to-severe atopic dermatitis, complementing clinician-reported efficacy and safety outcomes.Clinical Trial RegistrationNCT02780167 (registered 23 May, 2016), NCT03349060 (registered 21 November, 2017), NCT03575871 (registered 3 July, 2018).
CONCLUSIONS: Childhood AD, particularly persistent disease with sleep disturbances, was associated with a wide range of behavioral problems in childhood and adolescence.PMID:33840782 | DOI:10.1097/DER.0000000000000749
CONCLUSIONS: Atopic dermatitis and AD severity are associated with SDs, which considerably impact quality of life and other health outcomes in adults with AD.PMID:33675326 | DOI:10.1097/DER.0000000000000731