Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation

Cell types in ventral midbrain are involved in diseases with variable genetic susceptibility, such as Parkinson ’s disease and schizophrenia. Many genetic variants affect regulatory regions and alter gene expre...
Source: Epigenetics and Chromatin - Category: Genetics & Stem Cells Authors: Tags: Research Source Type: research