The Application of Targeted RNA Sequencing for KMT2A –Partial Tandem Duplication Identification and Integrated Analysis of Molecular Characterization in Acute Myeloid Leukemia

In this study, we developed a targeted RNA-based next-generation sequencing panel, together with single primer enrichment and unique molecular identifiers, to identify KMT2A-PTD as well as AML-related gene fusions and other driver mutations.

Source: Journal of Molecular Diagnostics - August 9, 2021 Category: Pathology Authors: Bing Dai, Hao Yu, Tingting Ma, Yichen Lei, Jiyue Wang, Yunxiang Zhang, Jing Lu, Han Yan, Lu Jiang, Bing Chen Tags: Regular article Source Type: research