Ultrasound Detects Ulcerative Colitis Disease Activity

FRIDAY, Aug. 27, 2021 -- A new ulcerative colitis intestinal ultrasound (UC-IUS) index shows strong correlation with endoscopy for detection of disease activity, according to a study published in the August issue of the Journal of Crohn's and...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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CONCLUSIONS: The Norwegian version of MFI-20 is valid, reliable and responsive. The instrument can safely be used in studies using fatigue as an endpoint.PMID:35076321 | DOI:10.1080/00365521.2022.2029939
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
Aging Clin Exp Res. 2022 Jan 25. doi: 10.1007/s40520-022-02076-1. Online ahead of print.ABSTRACTThe prognostic impact of inflammatory bowel disease (IBD), chronic inflammatory conditions consisting of ulcerative colitis (UC), and Crohn's disease (CD) on the risk of dementia has been poorly investigated. We evaluated the risk of dementia in IBD patients by a systematic review and meta-analysis of the available data. Three studies, enrolling 121.827 patients [14.839 IBD (12.1%) and 106.961 (87.7%) controls, respectively] were included in the analysis. Of these, 57.7% (n = 8.571) had UC, while 42.2% (n = 6268) had CD. The mea...
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Source Type: research
World J Gastroenterol. 2021 Dec 21;27(47):8047-8057. doi: 10.3748/wjg.v27.i47.8047.ABSTRACTInflammatory bowel disease (IBD) is a chronic condition that requires continuous medical treatment. To date, the medical management of patients with moderately-to-severely active IBD who develop dependence or resistance to corticosteroids is based on immunomodulator drugs. Such therapies are licenced after passing through three phases of randomized controlled trials (RCTs), and are subsequently adopted in clinical practice. However, the real-life population of IBD patients who require these therapies can significantly differ from tho...
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
World J Gastroenterol. 2021 Dec 21;27(47):8040-8046. doi: 10.3748/wjg.v27.i47.8040.ABSTRACTHelicobacter pylori (H. pylori) infection causes changes to the intestinal flora, such as small intestinal bacterial overgrowth, and increases gastric acid secretion-stimulating gastrointestinal hormones, mainly gastrin, due to a decrease in gastric acid caused by atrophic gastritis. In addition, the cellular components of H. pylori travel through the intestinal tract, so the bacterial infection affects the immune system. Therefore, the effects of H. pylori infection are observed not only in the stomach and the proximal duodenum but ...
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
In conclusion, IL-38 may play an anti-inflammatory and protective role in the pathophysiology of IBD, in particular ulcerative colitis, through the suppression of IL-36-induced inflammatory responses.PMID:35068683 | PMC:PMC8764106 | DOI:10.3164/jcbn.21-104
Source: Clinical Biochemistry - Category: Biochemistry Authors: Source Type: research
CONCLUSIONS: In this large study among older adults (≥66 years of age), IBD was positively associated with gastrointestinal cancers. Associations with extraintestinal cancers may reflect the effect of immunosuppressive medications.PMID:35071980 | PMC:PMC8767622 | DOI:10.1093/jncics/pkab096
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research
World J Gastroenterol. 2021 Dec 21;27(47):8047-8057. doi: 10.3748/wjg.v27.i47.8047.ABSTRACTInflammatory bowel disease (IBD) is a chronic condition that requires continuous medical treatment. To date, the medical management of patients with moderately-to-severely active IBD who develop dependence or resistance to corticosteroids is based on immunomodulator drugs. Such therapies are licenced after passing through three phases of randomized controlled trials (RCTs), and are subsequently adopted in clinical practice. However, the real-life population of IBD patients who require these therapies can significantly differ from tho...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
World J Gastroenterol. 2021 Dec 21;27(47):8040-8046. doi: 10.3748/wjg.v27.i47.8040.ABSTRACTHelicobacter pylori (H. pylori) infection causes changes to the intestinal flora, such as small intestinal bacterial overgrowth, and increases gastric acid secretion-stimulating gastrointestinal hormones, mainly gastrin, due to a decrease in gastric acid caused by atrophic gastritis. In addition, the cellular components of H. pylori travel through the intestinal tract, so the bacterial infection affects the immune system. Therefore, the effects of H. pylori infection are observed not only in the stomach and the proximal duodenum but ...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
World J Hepatol. 2021 Dec 27;13(12):1828-1849. doi: 10.4254/wjh.v13.i12.1828.ABSTRACTHepatobiliary disorders are among the most common extraintestinal manifestations in inflammatory bowel diseases (IBD), both in Crohn's disease and ulcerative colitis (UC), and therefore represent a diagnostic challenge. Immune-mediated conditions include primary sclerosing cholangitis (PSC) as the main form, variant forms of PSC (namely small-duct PSC, PSC-autoimmune hepatitis overlap syndrome and IgG4-related sclerosing cholangitis) and granulomatous hepatitis. PSC is by far the most common, presenting in up to 8% of IBD patients, more fr...
Source: World Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research
World J Gastroenterol. 2021 Dec 21;27(47):8047-8057. doi: 10.3748/wjg.v27.i47.8047.ABSTRACTInflammatory bowel disease (IBD) is a chronic condition that requires continuous medical treatment. To date, the medical management of patients with moderately-to-severely active IBD who develop dependence or resistance to corticosteroids is based on immunomodulator drugs. Such therapies are licenced after passing through three phases of randomized controlled trials (RCTs), and are subsequently adopted in clinical practice. However, the real-life population of IBD patients who require these therapies can significantly differ from tho...
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
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