Tartrate ‐resistant acid phosphatase type 5/ACP5 promotes cell cycle entry of 3T3‐L1 pre‐adipocytes by increasing IGF‐1/Akt signaling

In conclusion, TRAP 5a increases proliferation of pre-adipocytes in a dose-dependent fashion by promoting entry into S-phase. Part of this effect is likely due to increased IGF-1 signaling through the Akt signaling pathway.

Source: FEBS Letters - August 21, 2021 Category: Biochemistry Authors: Pernilla L ång, Christina Patlaka, Göran Andersson Tags: RESEARCH LETTER Source Type: research