P –342 Are blastulation and clinical pregnancy rates in women with endometriomas different than those without?

AbstractStudy questionDoes the presence of endometrioma during ovarian stimulation affect blastulation and clinical pregnancy rates (CPR)?Summary answerBlastulation rates were similar in women with endometrioma compared to women without. Likewise, CPR were comparable.What is known alreadyAlthough relationship of endometriosis and subfertility is well-established, its mechanism is still under investigation. Decreased oocyte quality, resulting from anatomical and/or inflammatory factors is one of the prominent culprits. Most studies regarding endometriosis and oocyte quality are highly heterogeneous and effect of endometriosis on oocyte quality is yet to be determined. Blastulation is thought as a surrogate marker for oocyte quality. Thus, it may be possible that detrimental effect of the presence of endometrioma during ovarian stimulation can be indirectly assessed by blastulation.Study design, size, durationRecords of all women who underwent assisted reproductive technology treatment at Koc University Hospital Assisted Reproduction Unit between 2016 and October 2020 were screened for this retrospective study. All women who had endometrioma(s) during ovarian stimulation were included in the study group (EG) (n  = 71). They were matched with women diagnosed with tubal factor or unexplained infertility who underwent oocyte pickup within the same period to form the control group (CG) (n = 104).Participants/materials, setting, methodsAll women underwent antagonist or long ...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research