P –155 Oocyte recovery 39 hours (from 39h to 41h) after administration of follicular maturation trigger does not affect clinical results

AbstractStudy questionWhat is the clinical outcome of oocytes recovered after 39  hours from ovulation inducing drug administration?Summary answerOocytes obtained after 39  hours from follicular maturation triggering are equally viable to those obtained at the standard time of 36 hrs.What is known alreadyIn the clinical setting of ART, ovum pick-up (OPU) is generally performed around 36  hours after the administration of ovulation inducing drugs (OID). However, there are cases where OPU cannot be performed at this time often due to long operating lists. As the time elapsed between the administration of ovulation inducing drugs and OPU becomes longer, there is a concern about time -related oocyte aging. Nevertheless, there are few reports of clinical results of OPU after 36 hours from OID.Study design, size, durationWe conducted a review of 1187 cycles and 1951 patients in which OPU and embryo transfer was performed in 2017 –2018. All cycles underwent a ‘freeze-all’ of embryos and the transfer cycle was in the thawed embryo transfer cycle for all cases.Participants/materials, setting, methodsThe time from the administration of OID to the end of OPU was divided into 36h group and over 39h group and the MII and normal fertilization rate of oocytes obtained from OPU after ovarian stimulation were compared. After confirmation of fertilization, the D3 good-quality embryo and the D5 and 6 good-quality blastocyst rates of embryos that continued to be cultured and the ...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research