Montelukast potentiates the antiinflammatory effect of NSAIDs in the rat paw formalin model and simultaneously minimizes the risk of gastric damage

ConclusionsWhile montelukast equally enhances antiinflammatory action of diclofenac or celecoxib via downregulating iNOS/COX2/LTs/IL-6 signaling, its gastroprotective action is preferentially potentiated by celecoxib.

http://link.springer.com/10.1007/s00011-021-01492-9

Source: Inflammation Research - August 11, 2021 Category: Research Source Type: research