The Role of Apolipoprotein E ε4 in Early and Late Mild Cognitive Impairment

Conclusions: AnAPOEε4 allele is associated with increased CSF tau and worse cognition in both EMCI and LMCI, and this association may be mediated by Aβ. We conclude thatAPOEε4 may be an important mediator of tau pathology and cognition in the early stages of AD.Eur Neurol
Source: European Neurology - Category: Neurology Source Type: research