Viruses, Vol. 13, Pages 1528: Lentiviral Vectors for T Cell Engineering: Clinical Applications, Bioprocessing and Future Perspectives

This article reviews the biological principles as well as the bioprocessing of lentiviral (LV) vectors and adoptive T cell therapy. Clinical and engineering successes, shortcomings and future opportunities are also discussed. The development of Good Manufacturing Practice (GMP)-compliant instruments, technologies and protocols will play an essential role in the development of LV-engineered T cell therapies.
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research