Laminin A Peptides

This invention relates to peptides and derivatives thereof having laminin-like activity, as well as a pharmaceutical composition of the peptide. The peptides claimed include Serine-Isoleucine-Lysine-Valine-Alanine-Valine (SIKVAV). Methods for promoting increased adhesion and migration of epithelial cells is also disclosed. The peptides have wide usage in research, nerve regeneration and cancer treatment. For example, this invention may be useful as an adhesion and regeneration agent for nerve guides and as an adhesion agent for vascular prosthesis.Inventors: Hynda Kleinman (NIDCR)Commercial Advantages:adhesion agentcancer therapeuticresearch reagentCompetitive Advantages:key extracellular matrix componentwidespread biological activity
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Tags: Research Materials Licensing Desired NIDCR Oncology Source Type: research