Influence of HIV infection on the distribution of high-risk HPV types among women with cervical precancerous lesions in Yaounde, Cameroon

Cervical cancer is most often caused by infection of the cervix by high-risk human papillomavirus (HPV) (He and He, 2019), a sexually transmitted virus that mostly infects women during their reproductive years (Kim et al., 2019). Approximately 90% of HPV infections are asymptomatic, controlled by the immune system, and cleared within two years. However, the remaining 10% may persist and progress to dysplasia and invasive carcinoma through a mechanism involving oncoproteins E6 and E7 and other co-carcinogens, and eventually a compromised immune system (Matovelo et al., 2012).

Source: International Journal of Infectious Diseases - July 28, 2021 Category: Infectious Diseases Authors: Richard TAGNE SIMO, Fonyuy B. KIAFON, Charlette NANGUE, Andr é P. GOURA, Jackson L. EBUNE, Moki C. USANI, Armel H. NWABO KAMDJE, Paul F. SEKE ETET, Phélix B. TELEFO Source Type: research