Corneal lymphangiogenesis in dry eye disease is regulated by substance P/neurokinin-1 receptor system through controlling expression of vascular endothelial growth factor receptor 3

CONCLUSIONS: SP/NK1R system promotes lymphangiogenesis in vitro and NK1R antagonism suppresses pathologic corneal lymphangiogenesis in DED in vivo.PMID:34311077 | DOI:10.1016/j.jtos.2021.07.003

Source: The Ocular Surface - July 26, 2021 Category: Opthalmology Authors: Seok Jae Lee Sang-Taek Im Jun Wu Chang Sik Cho Dong Hyun Jo Yihe Chen Reza Dana Jeong Hun Kim Sang-Mok Lee Source Type: research