Emergence of SARS-COV-2 Spike Protein Escape Mutation Q493R after Treatment for COVID-19

We report in vivo selection of a severe acute respiratory syndrome coronavirus 2 spike mutation (Q493R) conferring simultaneous resistance to bamlanivimab and etesivimab. This mutation was isolated from a patient who had coronavirus disease and was treated with these drugs.PMID:34314668 | DOI:10.3201/eid2710.211538

Source: Emerging Infectious Diseases - July 27, 2021 Category: Infectious Diseases Authors: Daniele Focosi Federica Novazzi Angelo Genoni Francesco Dentali Daniela Dalla Gasperina Andreina Baj Fabrizio Maggi Source Type: research