Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer ’s disease

Disease-associated microglia (DAMs), that surround beta-amyloid plaques, represent a transcriptionally-distinct microglial profile in Alzheimer ’s disease (AD). Activation of DAMs is dependent on triggering rec...

Source: Molecular Neurodegeneration - July 23, 2021 Category: Neurology Authors: Christel Claes, Emma Pascal Danhash, Jonathan Hasselmann, Jean Paul Chadarevian, Sepideh Kiani Shabestari, Whitney E. England, Tau En Lim, Jorge Luis Silva Hidalgo, Robert C. Spitale, Hayk Davtyan and Mathew Blurton-Jones Tags: Short report Source Type: research