Active dendrites enable strong but sparse inputs to determine orientation selectivity [Neuroscience]

The dendrites of neocortical pyramidal neurons are excitable. However, it is unknown how synaptic inputs engage nonlinear dendritic mechanisms during sensory processing in vivo, and how they in turn influence action potential output. Here, we provide a quantitative account of the relationship between synaptic inputs, nonlinear dendritic events, and action...

Source: Proceedings of the National Academy of Sciences - July 23, 2021 Category: Science Authors: Lea Goetz, Arnd Roth, Michael Hausser Tags: Neuroscience Biological Sciences Source Type: research