Knock-in models related to Alzheimer ’s disease: synaptic transmission, plaques and the role of microglia

Microglia are active modulators of Alzheimer ’s disease but their role in relation to amyloid plaques and synaptic changes due to rising amyloid beta is unclear. We add novel findings concerning these relations...

Source: Molecular Neurodegeneration - July 15, 2021 Category: Neurology Authors: Diana P. Benitez, Shenyi Jiang, Jack Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Natalie Wong, Katie M. Stringer, Karina S. Vitanova, Victoria C. Smith, Dhaval Joshi, Takashi Saito, Takaomi C. Saido, John Hardy, J örg Hanrieder, Bart De Strooper & h Tags: Research article Source Type: research