Prognostic Impact of Concurrent DNMT3A, FLT3 and NPM1 Gene Mutations in Acute Myeloid Leukemia Patients

Acute myeloid leukemia (AML) is one of the rapidly progressing malignancies which is characterized by unregulated proliferation of hematopoietic precursors .Technological improvements enhanced the availability of genetic AML biomarkers. The clinical relevance of these molecular markers for AML diagnosis, planning of therapy and risk stratification are increasing evidently.

Source: Clinical Lymphoma, Myeloma and Leukemia - July 15, 2021 Category: Hematology Authors: Heba Allah E Abd Elrhman, Yomna M El-Meligui, Saffaa M Elalawi Source Type: research