Subcutaneous Fat Necrosis associated with hypercalcemia in neonates with neonatal encephalopathy treated with therapeutic hypothermia

Subcutaneous fat necrosis of the newborn (SFNN) is a rare, self-resolving panniculitis. The onset of skins lesions occurs within the first week of life, with a median age of onset around day 6 of life (range 1-70). About 50 % of neonates with SFNN will develop hypercalcemia in the first month though some present later. Typically, SFNN develops prior to hypercalcemia. Only half of the neonates have classic symptoms of hypercalcemia; routine screening for hypercalcemia is recommended for neonates with SFNN or at-risk.

Source: Seminars in Fetal and Neonatal Medicine - July 14, 2021 Category: Perinatology & Neonatology Authors: Celia Rodd, Agnes Schwieger, Cornelia Hagmann, Newborn Brain Society Guidelines and Publications Committee Source Type: research