Compliance with Telemonitoring in Heart Failure. Are Study Findings Representative of Reality?: A Narrative Literature Review
Telemedicine and e-Health, Ahead of Print.
Condition: Heart Failure With Preserved Ejection Fraction Interventions: Drug: Metformin; Drug: Placebo Sponsors: Wake Forest University Health Sciences; Atrium Health; University of South Florida Not yet recruiting
Condition: Chronic Heart Failure With Reduced Ejection Fraction Interventions: Drug: Vericiguat; Drug: Placebo Sponsor: Merck Sharp & Dohme Corp. Not yet recruiting
Condition: Heart Failure Interventions: Drug: Furosemide; Drug: Torsemide Sponsor: Yale University Recruiting
Conclusion. The use of a HF virtual patient simulation was associated with improved examination performance and was well received by student users.PMID:34697012 | DOI:10.5688/ajpe8650
AbstractChronic thromboembolic pulmonary hypertension is an underdiagnosed condition. Patients typically present with the symptoms of right heart failure. Diagnosis is usually done by radionuclide ventilation/perfusion (VQ) scan, high-quality multidetector computed tomography (CT) or pulmonary angiography at expert centers. Pulmonary endarterectomy remains the corner stone in management of chronic thromboembolic pulmonary hypertension. Deep hypothermic circulatory arrest is commonly used for the operation at most centers. In-hospital mortality ranges from 1.7 to 14.2%. Pulmonary hemorrhage, reperfusion lung injury, and rig...
Cell Death &Disease, Published online: 26 October 2021; doi:10.1038/s41419-021-04282-7Cardiac-specific CGI-58 deficiency activates the ER stress pathway to promote heart failure in mice
Future Cardiology, Ahead of Print.
ConclusionsResults indicated relative superiority of TPNS and ASV to BPAP-BUR and CPAP in their effects on AHI and ESS.
Vasopressin (AVP) is a key neurohormone involved in the regulation of body functions. Due to its urine-concentrating effect in the kidneys, it is often referred to as antidiuretic hormone. Besides its antidiuretic renal effects, AVP is a potent neurohormone involved in the regulation of arterial blood pressure, sympathetic activity, baroreflex sensitivity, glucose homeostasis, release of glucocorticoids and catecholamines, stress response, anxiety, memory, and behavior. Vasopressin is synthesized in the paraventricular (PVN) and supraoptic nuclei (SON) of the hypothalamus and released into the circulation from the posterio...
The genetic background of congenital heart diseases (CHDs) is extremely complex, heterogenous, and still majorly to be determined. CHDs can be sporadic or familial. In this article we discuss in detail the phenotypic spectrum of selected genes including MYH7, GATA4, NKX2-5, TBX5, and TBX20. Our goal is to offer the clinician a general overview of the clinical spectrum of the analyzed topics that are traditionally known as causative for CHDs but we underline in this review the possible progressive functional (cardiomyopathy) and electric aspects (arrhythmias) caused by the genetic background.