Salivary IL-8 as a putative predictive biomarker of radiotherapy response in head and neck cancer patients

ConclusionsAfter analyzing the panel of salivary cytokines, IL-8 showed the best association to the response to radiotherapy; in this sense, low IL-8 levels in the saliva of HNC patients before receiving irradiation therapy are associated with positive RT outcomes.Clinical relevanceSalivary IL-8 expression in HNC patients undergoing RT may serve as a potential predictive biomarker of response to the treatment.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research